Objective:To explore the correlation factors of influencing the effect of mifepristone and misoprostol in artificial abortion .Methods:600 cases of women with early pregnancy who volunteered to ask medicinally abortion were chosen .The women were divided into two group: control group ( 487 women who succeeded in medicinally abortion ) , observation Group ( 113 women who didn ’ t succeed in medicinally abortions).Compared to their general information ( height, weight and so on ), age, perimenopause, the gestationail sac diameter ,germ,the position of the uterus and chronic peivic infiammatory disease , pregnancy , chiidbirth history , cesarean section and uterine fibroids .Results:The infiuencing factors of the results after medical abortion were abortion ,menopause,time,the gestationai sac diameter ,germ,the position of the uterus and chronic peivic infiammatory disease ( P <0.05 ).but there was no siegnificant difference of age , pregnancy ,chiidbirth history , cesarean section and uterine fibroids in two groups .The danger degree of those indexes from high to low were germ , the gestationail sac diameter >2.3 cm, chronic peivic infiammatory disease ,uterine position , time >40 d in sequence .Conclusion:A variety of factors are related to medical failure,so should have the gynecologic examinations before medicine abortion ,and choose the proper method for induced abortion in order to reduce the harm of women in pregnant .%目的：探究影响米非司酮联合米索前列醇进行人工计划流产效果的相关因素。方法：选择2012年3月至2013年8月在我院自愿实施药物流产的600名7周内早孕孕妇，将药物流产成功的487例设为对照组，将药物流产失败的113例设为观察组。对比2组的一般资料（身高、体质量等）、年龄、停经时间、孕囊大小、胚芽、孕次、分娩史、流产史、剖宫史、子宫位置和合并慢性盆腔炎症，探究影响药物流产效果的相关因素。结果：2组孕妇身高、体质量、年龄比较无显著性差异（ P＞0.05）；而停经时间、孕囊大小、胚芽、子宫位置、合并慢性盆腔炎和流产史比较有显著性差异（P＜0.05），且药物流产失败危险程度依次为有胚芽、孕囊＞2.3 cm、合并慢性盆腔炎、子宫位置平位、子宫位置后位、停经时间＞40 d。而年龄、孕次、分娩史和剖宫史不是米非司酮联合米索前列醇进行人工计划流产失败的危险因素。结论：米非司酮联合米索前列醇进行人工计划流产效果是受多因素影响的，流产前要做好检查，选择合适的流产方法，避免药物流产失败和降低药物流产对孕妇的伤害。
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