Mycoplasma penumoniae ( MP) is a common pathogenic microorganisms that causes respiratory infections, and PI protein is a transmembrane protein associated with adhesion, the adhesion is the important reason that causes inflammation. Currently, a new discovery of isolate 3 known as PI variants have drawn wide attention among scholars. In addition, PI protein can also be prepared for the laboratory diagnosis of MP infection. Therefore, the study of PI protein in the fields of structure gene, pathogenesis and laboratory diagnosis is of great significance.%肺炎支原体(MP)是引起呼吸系统感染常见的病原微生物,P1蛋白是肺炎支原体上一种与黏附相关的跨膜蛋白,其黏附作用是引发炎症作用的重要原因.目前新发现的一种被称为孤立岛3的P1变异体引起了各学者的广泛关注.另外,还可以利用P1蛋白进行MP感染的实验室诊断.因此,探讨P1蛋白基因结构、致病机制和实验室诊断方法具有重要意义.
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