血清降钙素原检测指导下呼吸道感染患者抗生素合理应用价值分析

摘要

Objective :Analysis of serum procalcitonin guidance for reasonable application of antibiotics in lower respir‐atory tract infection in patients with value .Methods :From 2012 December to my courtyard department of Pediatrics in 2013 December were treated 160 cases of patients with lower respiratory tract infection .The patients were divided into two groups randomly ,the control group were treated with the standard antibiotic treatment ,the observation group in the procalcitonin guidance given antibiotic treatment ,compared 2 groups of patients with treatment effect .Results:In cough ,fever ,cough ,asthma ,lung wet rales and other clinical symptoms and signs disappeared time ,the observation group and the control group were not statistically significant ,P<0 .05 ,however ,the observation group use of antibi‐otics ,antibiotic use average time ,average hospitalization time and average hospitalization expenses were significantly lower than those in the control group patients ,the difference was statistically significant ,P<0 .05 .Conclusion:Serum procalcitonin results can well guide clinicians to regulate the use of antibiotics ,reduce hospitalization time ,cost of hos‐pitalization ,therefore ,in clinical work ,we can consider the application of antibiotics in patients with monitoring drop procalcitonin level to better ,do have a definite object in view .%目的：分析血清降钙素原检测指导下呼吸道感染患者抗生素合理应用价值。方法：研究对象来自我院儿科2012年12月－2013年12月收治的160例下呼吸道感染患者。采用随机分组的方式将患者分为两组，对照组患者给予标准抗生素治疗，观察组则在降钙素原指导下给予抗生素治疗，比较2组患者治疗效果。结果：在发热、咳嗽、咳痰、气喘、肺部干湿性啰音等临床症状和体征消失平均时间方面，观察组和对照组患者差异无统计学意义，P＜0．05，但是，观察组抗生素使用率、抗生素使用平均时间、平均住院时间和平均住院费用均显著低于对照组患者，差异有统计学意义，P＜0．05。结论：血清降钙素原监测结果能够很好的指导临床医师规范使用抗生素，有效的减少住院时间、住院费用，为此，在临床工作中，可以考虑通过监测患者血清降钙素原水平来更好的应用抗生素，做到有的放矢。