CT、MRCP、US联合血清CA19-9、CEA诊断壶腹周围癌的价值

摘要

目的 探讨CT、MRCP、US检查联合血清CA19-9、CEA的检测对壶腹周围癌的诊断价值.方法 分析87例经手术或经内镜逆行性胰胆管造影术(endoscopic retrograde cholangio-pancreatography,ERCP)活检病理证实壶腹周围癌患者的CT、MRCP、US的影像学表现及血清CA19-9、CEA检测结果.探讨CT、MRCP、US检查联合血清CA19-9、CEA检测对壶腹周围癌的早期诊断价值.结果 ①CT、MRCP检查壶腹周围癌优于US检查;②87例壶腹周围癌血清CEA的差异有统计学意义(x2=9.97,P＜0.05),CA19-9差异无统计学意义(x2=2.11,P＞0.05);③CT、MRCP、US检查与血清CA19-9、CEA检测的联合使壶腹周围癌的诊断准确率得到提高.结论 CT、MRCP、US检查联合血清CA19-9、CEA检测可以提高壶腹周围癌的早期诊断水平,为临床制定治疗方案提供帮助.%Objective To study the diagnostic value of computer tomography(CT),magnetic resonance cholangiopancreatography (MRCP),ultrasonography combined with serum CA19-9 and CEA for periampullary carcinomas.Methods We analyd the imaging findings and laboratory testings of 87 patients with periampullary carcinomas which were confirmed by surgical or biopsy specimen of ERCP.Results ①CT or MRCP was better than US in diagnosing periampullary carcinomas.② There was significant differences in serum CEA between four categories of periampullary carcinomas (x2 =9.97,P ＜ 0.05),while the serum CA19-9 had no statistical difference.③CT,MRCP,US combined with serum CA19-9 and CEA improved the diagnostic accuracy of the periampullary carcinomas.Conclusion CT,MRCP,US combined with serum CA19-9 and CEA can improve the early diagnosis of periampullary carcinomas and help for clinical treatment plan.