Objective Spine is the most common site of osseous tumor spread . Spine metastases are associated with obvious symptoms of back pain , sensory deficits, and weakness of extremities. They are responsible for a large part of the decreased quality of life experienced by patients with cancer metastasis . This study is to determine the effectiveness and safety of CyberKnife radiosurgery for spinal metastases. Methods From March 2009 to December 2011 , we treated 24 patients with 38 spinal metastases by Cy — berKnife radiosurgery, including 4 in the cervical, 21 in the thoracic , 9 in the lumbar, and 4 in the sacral vertebrae. Nine of the patients had received radiotherapy previously. We followed up the patients for pain palliation and adverse reaction . Results The patients were followed up for 1 to 25 (mean 12.5) months, during which 18 of patients were alive , 90% experienced palliation of pain , and none developed therapy related spinal injury. Conclusion CyberKnife radiosurgery is effective and safe for spinal metastasis .%目的 脊柱转移是恶性肿瘤骨转移的常见部位,脊柱转移患者常常伴有明显的背部疼痛及感觉、运动障碍,是恶性肿瘤患者生活质量下降的主要因素之一,本研究拟评估射波刀立体定向放射外科治疗脊柱转移瘤的临床效果及安全性.方法 2009年3月至2011年12月行射波刀立体定向放射外科治疗脊柱转移瘤患者24例,治疗病灶38处,其中颈椎4处,胸椎21处,腰椎9处,骶椎4处,有放疗史患者9例.比较治疗前后的疼痛缓解等情况,定期随访疗效及毒副反应.结果在随访12.5个月后(1～25月),生存18例,90%的患者疼痛治疗有效,随访期间内未见放射性脊髓病的发生.结论 射波刀立体定向放射外科治疗脊柱转移瘤是安全而有效的.
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