肥厚型心肌病MRI延迟强化率与心源性猝死风险的相关性分析

摘要

Objective To investigate the correlation between the rate of late gadolinium enhancement (LGE) and risk of sudden cardiac death in hypertrophic cardiomyopathy (HCM) patients. Methods 45 HCM patients and 20 normal volunteers underwent cardiac cine MRI and late gadolinium enhancement. Then, we calculated their rate of LGE and analyzed the difference between the two groups of data; The HCM Risk-SCD was used to calculate the 5 year SCD risk score of HCM patients, and to analyze the correlation between LGE rate and 5-year SCD risk score. Results The LGE rate of HCM patients was significantly higher than that of normal controls (P<0.001). The LGE rate of HCM patients was positively correlated with the 5-year SCD risk score (P<0.0001). Conclusion LGE rate is positively correlated with SCD risk in HCM, and can be used as a quantitative index to evaluate the SCD risk in HCM patients.%目的 探讨肥厚型心肌病 (HCM) 延迟强化 (LGE) 率与心源性猝死 (SCD) 风险的相关性.方法 选取我院确诊的45例HCM患者及20例健康志愿者, 两组均行磁共振延迟增强检查, 并计算LGE率, 对两组数据进行对比分析;用SCD事件风险评估模型计算HCM患者的5年SCD风险评分, 分析LGE率与5年SCD风险评分的相关性.结果 HCM患者LGE率明显大于正常对照组 (P<0.001), 并与5年SCD风险评分呈正相关 (P<0.0001) .结论 HCM患者LGE率与5年SCD风险呈正相关, LGE率可作为评估HCM患者SCD风险的量化指标.