老年轻度认知障碍患者血脂、叶酸、维生素B12和甲状腺激素水平的临床研究

摘要

目的：研究老年轻度认知障碍患者血脂、叶酸、维生素 B12、甲状腺激素水平之间的关系。方法：选择2012年7月~2014年9月住院的患者360例,分为MCI组、AD组、对照组,各110、120、70例,比较上述物质的水平。结果：MCI、AD组LDL-C、TC水平比对照组高,维生素B12、叶酸、FT3、T3水平比对照组低,AD组 TSH 比对照组低,MCI 组 TSH 比 AD组高,差异有统计学意义(P<0.05)。结论：TSH 对MCI转 AD 检测具有参考价值,补充叶酸、维生素 B12、降低血脂、保持甲状腺功能正常可能能够防治MCI、AD。%Objective:To study the relationship among the level of blood lipid folic acid,vitamin B12 and thyroid hormone of the elderly patients with mild cognitive impairment.Methods:Select 360 patients hospital-ized during the period from July 2012 to September 2014,,divided them into MCI group AD group and con-trol group,the case in each group were 110,120,70 respectively,compare the level of the components a-bove.Results:In MCI group and AD group ,the level of LDL-Cand TC were higher than that of the control group,the level of vitamin B12,folic acid,FT3 and T3 were lower than that of the control group,the level of TSH of AD group was lower than that of control group,while that of the MCI group was higher than that of the AD group,the difference was statistically significant (P<0.05).Conclusion:TSH can be taken as an reference to detect the transformation from CI to AD detection ,it helps to complement folic acid and vitamin B12,lower the level of blood lipid,maintain normal thyroid function ,prevent and cure MCI and AD.