A 型肉毒毒素注射联合康复训练治疗脑卒中后上肢痉挛的疗效观察

摘要

Objective:To analyze the clinical effects ofbotulinum toxin A injections combined rehabilita-tion training in the treatment of upper limb spasm after cerebral apoplexy.Methods:68 cases of patients with upper limb spasm after cerebral apoplexy treated in a hospital from January 2013 to February 2015 were se-lected and randomly divided into observation group (34 cases)and control group (34 cases).The control group was given conventional rehabilitation training,and the observation group was given botulinum toxin A injections therapy on the basis of control group.Then compared the therapeutic effect of two groups.Results:After 12 weeks treatment,the Ashworth spasm scale score of patients in observation group was(1.41±0.20), and that of control group respectively was (2.40±0.21).The modify-Barthel score of patients in observation group was significantly better than that of control group,and the difference was statistically significant (P <0.05).Conclusion:For patients with upper limb spasm after cerebral apoplexy,on the basis of conventional re-habilitation training combined botulinum toxin A injections can effectively improve patients'spasm degree, and improve patient's quality of life,which is worthy of popularization and application.%目的：：观察分析 A 型肉毒毒素注射联合康复训练治疗脑卒中后上肢痉挛的临床疗效。方法：选择2013年1月~2015年2月期间在某院进行治疗的68例脑卒中后上肢痉挛患者为研究对象，随机将患者分为观察组(34例)、对照组(34例)，对对照组患者常规进行康复训练，观察组患者联合 A 型肉毒毒素注射治疗，对比两组患者的治疗效果。结果：治疗12周后，观察组患者的 Ash-worth 痉挛量表评分为(1.41±0.20)分，对照组为(2.40±0.21)分，组间对比，观察组患者的改良 Barthel 指数评分显著高于对照组，差异具有统计学意义(P <0.05)。结论：对于脑卒中后上肢痉挛的患者来说，在常规康复训练治疗基础上联合 A 型肉毒毒素注射可有效改善患者痉挛程度，提高患者的生活质量，值得进行推广应用。