槟榔的化学成分

摘要

The chemical constituents of 95 %ethanolic extract of the fruits of Areca catechu were sep-arated and purified by silica gel,ODS and Sephadex LH-20 column chromatographies.Their structures were determined by chemical and spectroscopic methods.Ten compounds were identified as (-)-epcate-chin (1),procyanidin B1 (2),procyanidin B2 (3),proanthocyanidin B7 (4),epicatechin-(4β→8)-epicatechin-(4β→8)-catechin (5),epicatechin-(4β→6)-epicatechin-(4β→8)-catechin (6),auran-tiamide acetate (7),aurantiamide (8),neoechinulin A (9),echinulin (10),respectively.Compounds 6~10 were isolated from this plant for the first time.The antiviral activities of compounds 6~10 were e-valuated.%应用硅胶柱、ODS 柱、Sephadex LH-20柱等色谱方法对槟榔种子的体积分数95％乙醇提取物石油醚及乙酸乙酯萃取部位进行分离纯化，根据理化性质与波谱数据鉴定化合物的结构，分别为：表儿茶素（1），原花青素B1（2），原花青素B2（3），原花青素B7（4），epicatechin-（4β→8）-epicatechin -（4β→8）-catechin （5），epicatechin-（4β→6）-epicatechin-（4β→8）-catechin （6），金色酰胺醇酯（7），aurantiamide （8），neoechinulin A （9），echinulin （10）。其中，化合物6～10为首次从该植物中分离得到。对分离得到的聚合鞣质类化合物1～6进行了初步的体外抗病毒活性测试。