脑组织UCP2的生物学特征及在体育科学中的应用前景研究

摘要

To explore the application prospect of UCP2 in sport science.Methods：By the method of combination the literature review and prospect analysis,this paper reviewed and analyzed the development of UCP2,and forecasts the application prospect of UCP2 in sport science.Results and Conclusions： UCP2 can directly limit free radical production,regulate ATP biogenesis,influence synaptic plasticity;UCP2 is intimately related to the pathogenesis of the Epilepsy,Parkinson＇s disease,Cerebral ischemia and Traumatic brain injury,Alzheimer＇s disease;and aging.UCP2 has a wide application prospect in sport science.The further study on UCP2 will deepen the research on influence of sports to brain tissue,s mitochondrias.It will provide theoretical basis for preventing and curing some brain diseases,aging,sports fatigue and altitude hypoxia trainings.%探讨UCP2在体育科学中的应用前景。方法：采用文献综述和前瞻性分析相结合,对UCP2研究进展进行回顾分析,并展望UCP2在体育科学中的应用前景。结果与结论：UCP2在限制活性氧的产生,调节ATP的产量和线粒体的生成,影响突触可塑性等方面具有重要作用;UCP2与癫痫、帕金森症、脑缺血和外伤性脑损伤、阿尔茨海默病等发病机制及衰老密切相关。UCP2在体育科学中具有广阔的应用前景,对UCP2进一步研究将有利于运动对脑组织线粒体影响的研究引向深入,为诸多脑疾病的防治、衰老、运动性疲劳、高原低氧训练的研究提供理论依据。