Objective To discuss the technical skill of super-selective catheterization for “one-way valve occlusion” of the common hepatic artery during transcatheter arterial chemoembolization (TACE). Methods A total of 128 patients with “one-way valve occlusion”of the common hepatic artery were enrolled in this study, who were admitted to authors’ department to receive TACE during the period from 2000 to 2011. The lesions included hepatocellular carcinoma (n = 110), cholangiocellular carcinoma (n = 3) and hepatic metastasis (n=15). “One-way valve occlusion”of the common hepatic artery occurred in 90 patients (70.3%, 90/128) after 2-5 times of TACE had been carried out, and in the other 38 patients (29.7%, 39/128) the “one- way valve occlusion” of the common hepatic artery was recognized at the initial TACE procedure. Super-selective hepatic catheterization was performed via the superior mesenteric artery (SMA) approach or celiac artery (CA) approach using coaxial micro-catheter catheterization technique. The success rate and fluoroscopy time of super-selective catheterization were recorded, and the results were compared between the two approaches. Results A total of 337 times of hepatic super-selection catheterization were performed in 128 patients, with a mean of 2.6 times for each case. The success rate was 100%. Of the 337 procedures, the catheterization was via CA approach in 148 (43.9%, 148/337) and via SMA approach in 189 (56.1%, 189/337). The mean fluoroscopy time in CA approach group was 3.2 minutes(ranged 1-6 minutes), and in SMA group was 15.3 minutes(ranged 5-40 minutes). The difference between the two groups was statistically significant (P < 0.05). Conclusion Super- selective hepatic catheterization for “one-way valve occlusion” of the common hepatic artery can be achieved through SMA approach or CA approach by using coaxial micro-catheter catheterization. Compared with SMA approach, the technique of hepatic catheterization through CA approach is much simpler and the fluoroscopy time is significantly shorter.%目的：探讨肝动脉化疗栓塞（TACE）时肝动脉单向活瓣患者的插管技术。方法收集2000-2011年在上海中山医院行TACE中存在肝动脉单向活瓣的患者128例，其中肝细胞癌110例，胆管细胞癌3例，转移性肝癌15例。90例（70.3%，90/128）患者出现肝动脉单向活瓣前曾行TACE 2~5次，38例（29.7%，38/128）患者为首次介入治疗患者。肝动脉插管采用微导管同轴导管技术经肠系膜上动脉和腹腔动脉途径进行，分别比较经这2种途径插管的成功率和平均透视时间。结果128例患者共进行了337次超选择性肝动脉插管（平均每例2.6次），成功337次，成功率为100%。337次插管中经腹腔动脉途径插管148次（43.9%，148/337），平均透视时间3.2（1~6）min；经肠系膜上动脉途径插管189次（56.1%，189/337），平均透视时间15.3（5~40）min。经腹腔动脉途径插管的平均透视时间明显少于经肠系膜上动脉途径的平均透视时间（P<0.05）。结论对肝动脉单向活瓣的患者，可采用同轴微导管技术经肠系膜上动脉和腹腔动脉2个途径进行超选择性肝动脉插管。与肠系膜上动脉途径相比较，经腹腔动脉途径插管操作更加简单，透视时间明显缩短。
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