首页> 外国专利> Composition for hepatic arterial chemoembolization using human serum albumin nanoparticles carrying an antitumor agent and method preparing thereof

Composition for hepatic arterial chemoembolization using human serum albumin nanoparticles carrying an antitumor agent and method preparing thereof

机译:使用携带抗肿瘤剂的人血清白蛋白纳米粒子进行肝动脉化疗栓塞的组合物及其制备方法

摘要

The present invention aims at dramatically increasing the effect of hepatic arterial chemoembolization by developing human serum albumin-based nanoparticles, which is a bioprotein that effectively carries adriamycin, instead of adriamycin, which is an anticancer drug used in hepatic arterial chemoembolization. The human serum albumin nanoparticles carrying the adriamycin not only intensively infiltrate the drug effectively into the cells but also have a synergistic effect that can induce a long-term therapeutic effect by utilizing the sustained drug release effect from the particles.
机译:本发明旨在通过开发基于人血清白蛋白的纳米颗粒来显着提高肝动脉化学栓塞的效果,所述人血清白蛋白基纳米颗粒是有效携带阿霉素的生物蛋白,而不是阿霉素霉素,阿霉素是在肝动脉化学栓塞中使用的抗癌药。携带阿霉素的人血清白蛋白纳米颗粒不仅有效地将药物有效地渗透到细胞中,而且具有协同作用,该协同作用可以通过利用从颗粒的持续药物释放作用来诱导长期的治疗作用。

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