等离子喷涂HA／Ti复合涂层研究

摘要

对等离子喷涂HA／Ti复合涂层进行模拟体液和体外细胞试验，以考察涂层的生物学性能．结果指出，涂层经模拟体液浸泡后，表面覆盖一层碳酸磷灰石(carbonate-apatite)，这表明涂层具有良好的生物活性．粗糙的涂层表面易于形成碳酸磷灰石．模拟体液的浓度太小或pH值太大，均会导致碳酸磷灰石层不能在涂层表面形成．体外细胞试验显示，成骨细胞能在涂层表面紧密贴壁并正常生长，显示涂层具有优良的生物相容性．%SBF test and cell culture in vitro were carried out to evaluate the biological properties of plasma sprayed HA/Ti composite coatings. Results obtained show that the coating surfaces will be covered by carbonate-apatite layer after being immersed in SBF for 1 day, which indicate that the composite coatings possess good bioactivity. Carbonate-apatite layer is inclined to form on the rougher coating surface. Low concentration and high pH value of SBF are harmful to the formation of carbonate-apatite layer. Excellent biocompatibility of the composite coatings can be confirmed by osteoblasts attaching firmly and growing well on the coating surface.