原发性干燥综合征合并间质性肺病肺功能与高分辨CT的相关性分析

摘要

目的 探讨原发性干燥综合征合并间质性肺病(PSS-ILD)肺功能与高分辨CT(HRCT)的相关性及早期诊断方法.方法 分析朝阳医院63例PSS-I L D患者的肺功能及HRCT.并根据HRCT结果将PSS-ILD组分为急性肺泡炎期和慢性肺间质2组.同时选出对照组60例均为正常体检者.将PSS-ILD组与对照组,2组PSS-ILD组分别进行肺功能结果的比较.结果 慢性肺间质和急性肺泡炎组患者的PEF%、PEF50%、PEF25%和TLC%低于正常组,而RV/TLC%高于正常组,统计学检验有意义;但是,这些参数在慢性肺间质和急性肺泡炎组患者之间不存在差异.慢性肺间质和急性肺泡炎组患者的VC%、FVC%、FEV1%和DLCO%低于正常组,慢性肺间质组的上述参数亦低于急性肺泡炎组.结论 PSS-ILD的发生发展与疾病活动性和严重性相关,对于PSS病人应尽早监测肺功能及HRCT的变化,能早期发现病变,为阻止晚期病变进一步恶化提供帮助.%Objective To explore primary dry syndrome merger between physical consumption (pss,lung function and high ild)distinguish ct(hrct)relevance and early diagnosis. Methods of Analysis as the hospital 63 cases,patients pss ild lung function and hrct.and in accordance with the result will be-hrct pss ild components of acute pancreatitis alveolus and chronic lungs.the stroma of 2 groups in the 60 cases are elected for a checkup. Pss ild group will be devoted to the two groups-ild pss,a group respectively. Results The lung function,The quality and between slower and chest patients with acute alveolus group pef％,72.73％ and pef25 pef50,tlc％ below the normal group, and the rv tlc％ higher than normal group,statistics for meaningful;however,these parameters between the quality of the lungs in the slow and acute pancreatitis alveolus there is no difference between the group of patients. Slow lung stroma and acute pancreatitis alveolus of the vc％,72.73％ and fvc，fevl dlco％ below the normal lung,slow stroma of the above argument is also acute pancreatitis alveolus group. Conclusion Pss-ild events and disease related activities and severity for pss,as soon as possible to monitor patients with lung function and hrct change,could find,early to prevent further deterioration in the late may help.