目的：观察凉血解毒方加减灌肠治疗宫颈癌放疗后并发放射性直肠炎的临床疗效。方法将80例宫颈癌放射性直肠炎患者随机分为观察组和对照组各40例，两组患者术后均给予西医常规治疗，观察组在常规治疗基础上，加用凉血解毒方加减灌肠治疗2周，比较两组治疗有效率、健康调查表（SF-36）得分及常见并发症发生率。结果观察组放射性直肠炎治疗有效率明显高于对照组(P＜0.05)，SF-36得分在角色限制、机体疼痛、健康状况、情绪职能、心理健康方面明显高于对照组（P＜0.05），常见并发症发生率明显低于对照组(P<0.05)。结论凉血解毒方加减灌肠治疗宫颈癌放射性直肠炎安全有效。%Objective To observe clinical efficacy of modified enema of Liangxue Jiedu presciption on treatment of patients with factitial proctitis after cervical carcinoma radiotherapy. Methods 80 patients with factitial proctitis after cervical carcinoma radiotherapy were randomly divided into the observation group and the control group, 40 cases in each group. The both group patients were given conventional western medicine therapy. The observation group was treated with modified enema of Liangxue Jiedu presciption for 2 weeks on the base of routine treatment. The efficiency, the score of health inventory (SF-36) and the incidence of adverse reactions were observed in two groups. Results The efficiency of the observation group was significantly higher than that in the control group (P<0.05). The health inventory score in role restriction, body pain, health status, emotional function and mental health in the observation group was significant higher than that in the control group (P<0.05). There is no obvious difference of common complication between the observation group and the control group (P>0.05). Conclusion The modified enema of Liangxue Jiedu presciption is a safety and effective method for treatment of factitial proctitis after cervical carcinoma radiotherapy.
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