臭氧消融术结合针灸治疗腰椎间盘突出症及对相关炎性因子的影响

摘要

目的 探讨臭氧消融术结合针灸治疗腰椎间盘突出症患者的临床疗效,以及对患者血清中炎性因子的影响.方法选取2015年1月至2016年6月我院收治的腰椎间盘突出症患者96例,采用随机数字表法分成对照组(48例)和观察组(48例),对照组进行臭氧消融术治疗,观察组在对照组的基础之前进一步针灸治疗,每两天1次,连续治疗1个月.治疗后,评估两组的临床疗效,以及治疗前后两组患者腰椎关节活动度、JOA和VAS评分,观察两组治疗前及治疗后患者血清中炎性因子IL-1β、TNF-α、IL-6含量变化情况.结果治疗后,对照组的总有效率为79.2%,观察组为93.8%,两组比较具有显著性差异(P<0.05).治疗后,两组患者JOA和VAS评分均较治疗前明显有所改善(P<0.05),且观察组改善情况要优于对照组(P<0.05).两组患者治疗后腰椎前屈、 后伸的幅度较治疗前明显得到改善(P<0.05),而且观察组的改善情况优于对照组(P<0.05).治疗后,两组患者血清中炎性因子IL-1β、TNF-α、IL-6含量较治疗前明显下降(P<0.05),且观察组炎性因子下降程度明显优于对照组(P<0.05).结论臭氧消融术结合针灸治疗腰椎间盘突出症疗效比单纯使用臭氧消融术治疗更佳,且还具有更显著的抗炎作用,可以作为一种混合微创手术推广.%Objective To explore the clinical effect of ozone ablation combined with acupuncture in treatment of lumbar intervertebral disc herniation and the effect on serum inflammatory factors. Methods 96 patients with lumbar interverte-bral disc herniation in our hospital from January 2015 to June 2016 were selected and randomly divided into the observa-tion group (48 cases) and the control group (48 cases). The control group was given ozone ablation, the patients in observa-tion group were treated with acupuncture on the basis of the control group, once every two days for one month. After treat-ment, the clinical efficacies, JOA and VAS between two groups were evaluated, activities of lumbar joints were measured, the changes of the levels of blood IL-1β,TNF-α,IL-6 in two groups before and after treatment were detected. Results After treatment, the total effective rates in the control group and observation group were 79.2% and 93.8%, respectively, there were differences between two groups (P<0.05). After treatment, scores of JOA and VAS in the two groups were improved (P<0.05), and the improvement of activities of lumbar joints in the observation group were statistically significant than the con-trol group (P<0.05). After treatment, the flexion and extension of lumbar spinal column in the two groups were improved (P<0.05), and the improvement in the observation group was superior to the control group (P<0.05). After treatment, the level of inflammatory factors IL-1β, TNF-α, IL-6 were lower than before treatment (P<0.05). Conclusion The ozone ablation combined with acupuncture shows better effect than the only used ozone ablation in treatment of lumbar intervertebral disc herniation, and has significant anti-inflammatory, which is worthy of promotion as a comprehensive minimally invasive surgery.