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Revaluation of Clopidogrel:Let the Data Speak for Themselves

     

摘要

Clopidogrel was believed to be superior to aspirin by the well-known CAPRIE trial.However,no other large clinical trials demonstrated the same results,but all focused on the combination use of clopidogrel with aspirin,and combination therapy in CREDO was called the "Emperor's New Clothes".However,no one overturned the results of these clinical trials by quantitatively analyzing them.We reviewed ten large-scale clinical trials about clopidogrel.On the basis of results of CAPRIE,CREDO and CHARISMA trials,we r...

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    Institute;

    of;

    Clinical;

    Pharmacology;

    Department;

    of;

    Pharmacology;

    Tongji;

    Medical;

    College;

    Huazhong;

    University;

    of;

    Science;

    and;

    Technology;

    Department;

    of;

    Radiology;

    Wuhan;

    General;

    Hospital;

    Guangzhou;

    Military;

    Command;

    School;

    of;

    Business;

    University;

    of;

    Nanjing;

    Department;

    of;

    Cardiology;

    Beijing;

    Anzhen;

    Hospital;

    The;

    Center;

    for;

    Drug;

    Evaluation;

    State;

    Food;

    and;

    Drug;

    Administration;

    of;

    China;

    Department;

    of;

    Neurology;

    Xiangya;

    Third;

    Hospital;

    Central;

    South;

    University;

    Beijing;

    Tiantan;

    Hospital;

    Cardiology;

    Center;

    Chaoyang;

    Hospital;

    Capital;

    University;

    of;

    Medical;

    Sciences;

    Department;

    of;

    Health;

    Toxicology;

    MOE;

    Key;

    Laboratory;

    of;

    Environmental;

    and;

    Health;

    Renmin;

    Hospital;

    of;

    Wuhan;

    University;

    Department;

    of;

    Pharmacy;

    the;

    First;

    Hospital;

    of;

    Shanxi;

    Medical;

    University;

    Department;

    of;

    Orthopedics;

    Department;

    of;

    Ophthalmology;

    Union;

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    College;

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    Pharmacy;

    Wuhan;

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    of;

    Otorhinolaryngology;

    PLA;

    General;

    Hospital;

    The;

    Second;

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  • 正文语种 CHI
  • 中图分类 神经系统药物;
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