核糖体失活蛋白及其在植物抗立枯丝核菌基因工程中的应用

摘要

核糖体失活蛋白( RIPs)是一类主要出现在植物中并具有rRNA N-糖苷酶活性的蛋白质，大体上分为Ⅰ型和Ⅱ型2类。介绍了RIPs在抗真菌活性、毒性和免疫原性方面的研究进展，并对其在抗立枯丝核菌植物基因工程方面的应用进行了综述。%Ribosome inactivating proteins( RIPs) ,which have been shown to exhibit rRNA N-glycosidase activity,are mainly present in plants. They are broadly classified into two groups:type Ⅰand type Ⅱ. In this review,their biological functions of toxicity to cells and animals,antigenicity and antifungal activity are discussed. In addition,the research advance in application of RIPs in plant transgenic engineering to enhance the hosts’ resistance to Rhizoctonia solani is presented.