中药治疗幽门螺杆菌相关性胃炎的随机对照试验

摘要

【目的】研究胃炎清胶囊(由黄连、蒲公英、佛手、三七、黄芪等中药组成)治疗幽门螺杆菌(HP)相关性慢性胃炎的临床疗效。【方法】采用随机对照方法，将126例患者按2∶1随机分为2组，其中治疗组83例，对照组43例，治疗组口服胃炎清胶囊，对照组口服德诺(枸橼酸铋)，6周为1疗程。【结果】治疗组的临床症状(如上腹胀痛等)改善、胃镜炎症改善的有效率、病理组织学炎症改善及HP清除率等疗效均优于对照组，并以脾胃湿热型疗效最好。【结论】胃炎清胶囊适用于幽门螺杆菌相关性慢性胃炎患者，尤适用于脾胃湿热型者。%【Objective】To assess the therapeutic effects of Weiyanqing Capsule(WC ) on Helicobacter pylori associated chronic gastritis (HPACG).【Methods】A rando mized controlled trial was carried out.One hundred and twenty-six cases of HPACG were randomly allocated to treatment group (Group A,83 cases) and control group (Group B,43).Th e treatment group was treated with WC orally and the control group with bismuth citrate,and the treatment course last 6 weeks.【Results】The clinical symptoms i n the treatment group such as epigastric distension,anorexia were much improved as compared with the control group.So did the findings of gastroscopy and histop athology.The elimination rate of Helicobacter pylori was higher than that in th e control group.The therapeutic effect of WC for the patients with spleen-stomach heat-dampness syndrome was the best.【Conclusion】WC is effective for HPACG pat ients and especially for those with spleen-stomach heat-dampness syndrome.