二维联合三维超声诊断胎儿脑沟脑回发育异常的临床应用价值

摘要

Objective To evaluate the value of two-dimensional combined with three-dimensional ultrasound (2D&3D-US) on diagnosing the dysplasia of the fetal cerebral sulcus and gyrus . Methods 2D-US was performed to record the growth of cerebral sulcus and gyrus of 66 fetuses ,who were suspicious central nervous system dysplastic . Then 3D-US were performed for volume scan in three orthogonal planes mode display and storage ,offline diagnostics ,and comparing the diagnosis and follow-up results . Results Compared to the follow-up or autopsy ,36 fetuses proved to be 2cerebral sulcus and gyrus dysplasia or combine with it . Of them ,10 fetuses were agyric ,26 fetuses were hypoplasia ,and the rest 30 fetuses were normal . The diagnose accordance rate of 2D&3D and 2D-US were 92 .42% (61/66)and 75 .76%(50/66) ,respectively . There was statistically significant difference between them (χ2 =6 .68 ,P<0 .01) . Conclusions 2D&3D-US could promote the accurate diagnosis in dysplasia of fetal cerebral sulcus and gyrus ,w hich has an important clinical value .%目的：探讨二维联合三维超声诊断胎儿脑沟脑回发育异常的应用价值。方法对疑有中枢神经系统畸形的66胎胎儿，行二维超声检测记录脑沟脑回发育情况，后行三维超声容积扫描，以三正交多平面模式显示并储存，下线诊断，并将诊断结果与随访结果进行比较。结果经随访或尸检证实36胎胎儿存在或合并有脑沟回发育异常（10胎脑沟回未发育，26胎脑沟回发育迟缓）；30胎正常。二维联合三维超声诊断符合率为92．42％（61/66），单纯二维超声诊断符合率为75．76％（50/66），两者有显著差异（χ2＝6．68，P＜0．01）。结论二维联合三维超声可提高胎儿脑沟脑回发育异常诊断的准确性，具有重要的临床应用价值。