目的：研究脑电双频指数和熵指数在老年患者硬膜外复合丙泊酚靶控静脉全麻中麻醉深度监测的可行性、准确性，并比较其优越性。方法选取择期行根治性全胃切除术的老年胃癌患者40例，均采用硬膜外复合丙泊酚靶控输注静脉全麻的麻醉方法，记录不同时间节点患者的心率（HR）、平均动脉压（MAP）、脑电双频指数（BIS）、反应熵（RE）、状态熵（SE）及停药后苏醒时间、拔管时间、手术时间、丙泊酚总用量、术中知晓的发生与否。结果应用阶梯式靶控输注丙泊酚诱导、术中维持及停药后BIS和RE、SE均随着意识变化而变化，2组之间差别无统计学意义。结论老年患者上腹部手术中施行硬膜外复合丙泊酚靶控输注静脉全麻时，BIS和RE、SE均可准确反映其麻醉深度。%Objective To compare the differences between entropy and bispectral indexes on mo‐nitoring the depth of anaesthesia for the elderly patients during the target‐controlled infusion (TCI) of propofol general anesthesia . Methods Fourty elderly patients undergoing elective abdominal surgery were studied . Anaesthesia was induced with epidural anesthesia combined with the target‐controlled infu‐sion (TCI) of propofol general anesthesia . Recording HR ,MAP ,BIS ,RE ,SE at different time ,also the emergence time and extubation time after discontinuation ,total operating time ,total dose of propofol ,and occurrence of the perioperative awareness . Results When applying ladder‐type target‐controlled infusion of propofol ,BIS and RE ,SE all changed with the conscious during induction ,maintenance and discontinua‐tion of propofol . There was no statistic difference between two groups . Conclusion In elderly patients with upper abdominal surgery in the implementation of epidural composite propofol target‐controlled infu‐sion w hen general anesthesia ,BIS and RE ,SE may reflect the depth of anesthesia ,at the depth of anes‐thesia monitoring ,entropy index and bispectral index are both effective .
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