疏肝益气养营汤治疗甲状腺功能亢进性心脏病的临床研究

摘要

目的 观察自拟疏肝益气养营汤对甲状腺功能亢进性心脏病的治疗作用并探讨其机制.方法 将96例甲亢性心脏病患者按随机数字表法分为观察组和对照组,对照组给予西医常规治疗,观察组在给对对照组基础上加用自拟疏肝益气养营汤,疗程为3个月.疗程结束后分析比较两组患者的治疗有效率、腹血清游离甲状腺素(FT4)、游离三碘甲腺原氨酸(FT3)、促甲状腺素释放激素(TSH)、超声心动图指标左室射血分数(LVEF)、舒张末期左室内径(LVEDD)、左室收缩末期内径(LVESD)及各组心律失常的治疗效果.结果 观察组总有效率为89.58％,明显高于对照组的75.00％ (P＜ 0.05);治疗后两组患者FT3、FT4、TSH、Pro-BNP、LVESD、LVEDD 、LVEF比较差异具有统计学意义(P＜ 0.05);两组患者的心房纤颤、房性早搏、室性早搏治疗有效率比较差异有统计学意义(P＜0.05).结论 本研究结果显示自拟疏肝益气养营汤在治疗甲状腺功能亢进性心脏病方面效果显著,优于单用西药治疗.%Objective:To study the therapeutic effect of Shugan Yiqi Yangying Decoction on hyperthyroid heart disease.Methods:96 patients with hyperthyroid heart disease were randomly divided into the observation group and the control group.The control group received routine Western medicine treatment,and the observation group added Shugan Yiqi Yangying Decoction.The course of treatment was 3 months.After treatment,the effective rates,FT3,FT4 and TSH of the two groups were analyzed and compared,as well as LVEF,LVEDD,LVESD and treatment effect of arrhythmia.Results:The total effective rate of the observation group was 89.58％,which was significantly higher than that of the control group (75.00％)(P＜ 0.05).After treatment,there was statistically significant difference in FT3,FT4,TSH,Pro-BNP,LVESD,LVEDD and LVEF between the two groups (P＜ 0.05).There was statistically significant difference in the effective rate of atrial fibrillation,atrial premature beat,ventricular premature beat between the two groups (P＜ 0.05).Conclusion:Shugan Yiqi Yangying Decoction is effective in the treatment of hyperthyroid heart disease,which is superior to western medicine.