Objective To explore the feasibility and safety of laparoscopic complete mesocolic excision (CME) in radical right hemicolectomy. Methods The clinical data of 63 cases undergoing radical right hemicolectomy with laparoscopic CME (28 cases) and open CME (35 cases) were analyzed. The operation time,bleeding volume,hospitalization time,postoperative complications and other clinical pathological characteristics were compared between the two groups. Results Laparoscopic CME group had a longer operation time compared with open CME group [(226 ±53) vs. (193 ±48) min,P=0.035], but reduced blood loss [(108±73) vs. (130±65 ml),P=0.006], reduced time to liquid diet [(3.3±1.4) vs. (4.1 ± 2.5)d,P=0.046] days and length of hospital stay [(11.2 ±3.8) vs. (15 ±7.3)d,P<0.001]. In addition, there were no significantly difference between number of lymph node dissection and postoperative complication rate (all P>0.05). Conclusion Through standardized learning, laparoscopic CME surgery could be safe and effective in municipal hospitals.%目的：探讨地市级医院开展腹腔镜下全结肠系膜切除术（CME）治疗右半结肠癌的安全性和有效性。方法回顾性分析本院2012年1月至2014年12月收治的腹腔镜CME手术（28例）和开腹CME手术（35例）患者的临床资料，对两组患者手术时间、术中出血量和住院时间、术后并发症等情况予以比较。结果腹腔镜CME组手术时间较开腹CME手术[（226±53） vs．（193±48） min]延长（P＝0．035），但是可以减少术中出血量[（108±73） vs．（130±65） ml，P＝0．006]、缩短术后进食流质时间[（3．3±1．4） vs．（4．1±2．5） d，P＝0．046]和住院时间[（11．2±3．8） vs．（15±7．3） d，P＜0．001]，而两组淋巴结清扫和术后并发症发生率方面并无明显差异（均P＞0．05）。结论经过规范化学习，腹腔镜下CME手术治疗右半结肠癌可以安全、有效地在地市级医院开展。
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