目的：研究吸烟与否及吸烟量与前列腺癌患者血清硒水平之间的关系。方法检测31例前列腺癌和46例前列腺增生患者的血清硒浓度，统计所有研究对象的吸烟史和吸烟量，分析吸烟史及吸烟量与血清硒浓度之间的关系。结果吸烟与前列腺癌的发生相关，吸烟量与前列腺癌患者血清硒浓度负相关。结论吸烟可能通过降低患者血清硒浓度从而诱发前列腺癌的发生。%Objective To explore the correlation between smoking and serum level of selenium in patients with prostate cancer,then verify the hypothesis that smoking can induce prostate cancer by lowering the serum selenium levels. Methods we detected the serum selenium concentration in 31 cases of prostate cancer and 46 cases of benign prostatic hyperplasia patients respectively,ana-lyzed the history of smoking and smoking quantity of all the research objects,then studied the rela-tionship between smoking or smoking quantity and serum selenium concentration. Results Pros-tate cancer was associated with smoking and smoking was negatively correlated with the serum sele-nium concentration in patients with prostate cancer. Conclusions Smoking may induce prostate cancer by the lowering serum selenium concentration in patients.
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