目的 探讨输尿管孤立性纤维性肿瘤(SFT)的临床病理特征和生物学行为.方法对临床发现的输尿管SFT的临床表现和病理学特征进行分析总结.结果 输尿管 SFT具有症状不明显、病情进展缓慢、临床上不易与输尿管其他良性肿瘤相鉴别的特点.免疫组化检测Vimentin、CD34、bcl-2为主要阳性标志物,S-100、CK、NSE、Actin阴性有助于与神经纤维、平滑肌及间皮源性肿瘤相鉴别.手术效果良好,随访未见复发或转移.结论 输尿管SFT是一种罕见的肿瘤,较独特的病理表现有助于诊断和鉴别诊断.治疗以手术切除为主,生物学行为不肯定,需长期随访.%Objective To study the clinical features and biological behavior of the ureter solitary fi-brous tumor (SFT). Methods A case of ureter SFT was analyzed. Results The ureter SFT has a slow disease progression and no obvious symptoms.The diagnosis was difficult to differ from other ureter benign tumors.Immunohistochemical makers of Vimentin,CD34,bcl-2 were positive,and other markers such as S-100,CK,NSE and Actin were helpful for differential diagnosis.Surgical resection is effective.No recurrence or metastasis was found after 3-year follow-up period. Conclusions The diagnosis of ureter SFT depends on the histological and immunohistochemical examination.Surgical resection is the main treat-ment.A long-term follow-up is necessary.
展开▼