[目的]比较精神分裂症患者与正常人血清中微量元素钙、铜、锌、镁、镉的含量差异.[方法]采用WFX-12型原子吸收分光光度计平行测定59例成年男性精神分裂症患者与30例健康成年男性血清中钙、铜、锌、镁、镉的含量.[结果]精神分裂症患者血清中钙、铜、锌含量显著低于正常人(P＜0.01),镉含量显著高于正常人(P＜0.01);不同年龄段精神分裂症患者血清中钙、锌、铜、镁含量无显著性差异(P＞0.05),血清中镉含量随着年龄增长而增加(P＜0.05);血清中微量元素含量与体重、病程长短均无相关性(P＞0.05).[结论]成年男性精神分裂症患者血清中钙、铜、锌、镉含量与健康成年男性存在差异,且镉的含量随着年龄增长而增加.%[Objective] To compare the differences of serum concentrations of trace elements including calcium(Ca), copper(Cu), zinc(Zn), magnesium(Mn) and cadmium(Cd) in schizophrenic patients and healthy adults. [Methods] WFX-12 atomic absorption spectrometer was used to determine Ca, Cu, Zn, Mn and Cd in serum of 59 adult male schizophrenic patients and 30 healthy adults. [Results] The serum concentrations of Zn, Cu, Ca in schizophrenic patients were significantly lower than those in healthy adults( P ＜0.01), while the concentration of Cd in schizophrenic patients was significantly higher than that in healthy adults( P ＜0.01). There were significant differences in Ca, Zn, Cu and Mn in serum of schizophrenic patients with different age( P ＞0.05). The content of Cd increased by aging( P ＜0. 05). There is no obvious relationship between the levels of serum trace elements and body weight or the course of disease( P ＞0.05). [Conclusion]There are differences in Ca, Cu, Zn and Cd in serum between adult male schizophrenic patients and healthy male adults. The content of Cd increases by aging.
展开▼
