外周血C反应蛋白及尿微量白蛋白在2型糖尿病合并尿路感染患者中的诊断价值

摘要

[Objective] To explore the diagnostic values of C‐reactive protein (CRP) and micro‐albumin (MA) in patients with type 2 diabetes mellitus (T2DM ) and urinary inflammation .[Methods] From March 2011 to December 2014 ,120 T2DM patients with urinary inflammation were recruited as study group .At the same time ,another 100 T2DM patients were selected as control group .The baseline data and levels of CRP and MA were compared between two groups .The diagnostic values of CRP ,MA and CRP+ MA were ana‐lyzed .[Results] Gender ,age ,blood pressure ,blood lipid and body mass index (BMI) had no inter‐group sta‐tistical differences ( P >0 .05) while fasting plasma glucose (FPG) and HbA1c showed inter‐group statistical differences ( P <0 .05) .CRP and MA had inter‐group statistical difference ( P<0 .05) .The sensitivities and specificities of CRP ,MA and CRP+MA were 99 .17% ,83 .00% ;85 .83% ,98 .00% ;85 .00% ,99 .00% re‐spectively .And the differences had statistical significance ( P<0 .05) .[Conclusion]CRP and MA are valua‐ble in the diagnosis of T2DM patients with urinary inflammation .%【目的】探讨外周血C反应蛋白（CRP）及尿微量白蛋白（MA）在2型糖尿病（T2DM ）合并尿路感染患者中的诊断价值。【方法】选取T2DM合并尿路感染的患者120例（观察组），另外选取同期T2DM 非感染患者100例（对照组），检测两组CRP和M A水平，分析其在T2DM 合并尿路感染患者中的诊断价值。【结果】观察组患者的 CPR 和 M A 水平均显著高于对照组，差异有统计学意义（ P ＜0．05）。CRP 敏感度99．17％，特异度83．00％；M A敏感度85．83％，特异度98．00％；CRP＋M A敏感度85．00％，特异度99．00％。【结论】CRP和M A在T2DM合并尿路感染患者中诊断价值高，值得临床推广。