目的 探讨阿奇霉素或者红霉素两种大环内酯类抗生素治疗婴幼儿支气管肺炎的临床价值.方法 将本院诊治的80例支气管肺炎患儿随机分成两组:对照组40例,采用红霉素治疗;实验组40例,采用阿奇霉素序贯疗法治疗.观察与比较两组的临床疗效、不良反应发生率、临床症状改善时间及住院时间.结果 实验组的总有效率显著性高于对照组(P<0.05);实验组的注射部位疼痛、恶心呕吐、腹痛、皮疹等不良反应发生率显著性低于对照组(P<0.05);实验组的退热时间、喘憋缓解时间、咳嗽好转时间、肺啰音消失时间、住院时间均明显短于对照组(P<0.05).结论 临床应用大环内酯类抗生素治疗婴幼儿支气管肺炎的临床疗效确切.%Objective To investigate the rlinirai value of azithromyrin or erythromyrin in the treatment of children with broncho-pneumonia. Methods 80 children with bronchopneumonia were randomly and evenly divided into two groups. The control group were treated with erythromycin, and the treatment group were given azithromyrin sequential therapy. The clinical efficacy, the incidence of adverse reactions, the time of clinical symptoms improvement and hospital stay were observed and compared between the two groups. Results The total effective rate in the treatment group was significantly higher than that in the control group ( P ＜0. 05 ). The incidence of complications, such as injection pain, nausea, bellyache, and rash, was obviously lower in the treatment group than in the control group ( P ＜ 0. 05 ). The time of lever clearance, wheezing and cough disappeared, pulmonary rales vanished, and hospital stay in the treatment group were significantly lower than those in the control group ( P ＜ 0. 05 ). Conclusion The clinical use of macrolide antibiotics has a la-vorable effect in the treatment of children with bronrhopneumonia.
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