Local treatment of ocular infections, using collyrium comprising solution of macrolide antibiotic in solution in oily vehicle, giving high drug levels in ocular tissues without causing irritation

摘要

Pharmaceutical composition for the Prevention and / or treatment of Eye Infections and to be used in local Application,It is presented in the form of an Eye Drop distribution in which an agent Class of macrolide antibiotic, azithromycin,This solution in an oil vehicle.This vehicle is particularly the kind of products mainly composed of Medium Chain Triglycerides.In which functions are entirely by alcohol of glycerol Esterified carboxylic acids of saturated hydrocarbons, whose Molecule contains 5 to 12 carbon Atoms.It is preferably linear Chain fatty acids containing 8 to 10 carbon ATOMS, as the caprylic acid and Capric acid.The composition is prpeara by a solution of the active Agent in the Oil Vehicle at a temperature no higher than 70 degrees C.