防仰卧疗法对阻塞性睡眠呼吸暂停低通气综合征的疗效研究

摘要

目的 探讨防仰卧疗法治疗阻塞性睡眠呼吸暂停低通气综合征的疗效.方法 选取我院2015年1月至2016年10月期间我院收治的阻塞性睡眠呼吸暂停低通气综合征患者200例作为研究对象,根据经济条件和自愿分组,分为防仰卧疗法组和CAPA治疗组,CAPA治疗组采用仰卧单水平呼吸机进行治疗,防仰卧疗法组予以课题组设计的防仰卧睡球、防仰卧枕头、侧卧俯卧抱枕等寝具进行防仰卧睡姿疗法治疗(简称防仰卧疗法),观察两组患者治疗前后IAH、LSaO2、ODI指标、Epworth评分、匹茨堡睡眠指数评分及血清IL-6、IL-18、TNF-α水平变化.结果 治疗后LSaO2明显升高,IAH指标、ODI指标、Epworth评分、匹茨堡睡眠指数评分及血清IL-6、IL-18、TNF-α水平均有明显降低,且防仰卧疗法组升高和降低较明显,差异具有统计学意义(P<0.05).结论 防仰卧疗法治疗阻塞性睡眠呼吸暂停低通气综合征效果理想,还可提高患者的睡眠质量,省钱,实用方便,临床应用前景广阔.%Objective To study the effect of supine therapy on obstructive sleep apnea hypopnea syndrome.Methods 200 patients with obstructive sleep apnea hypopnea syndrome (OSAHS) from January 2015 to October 2016 in our hospital were randomly divided into two groups according to the economic condition and voluntary.The CAPA treatment group was treated with single-level ventilator, and the anti-supine therapy group was treated with supine sleeping-bed, anti-supine pillow, supine pillow and other bedding.The levels of IAH, LSaO2, ODI, Epworth score, Pittsburgh sleep index and serum IL-6, IL-18 and TNF-α were measured before and after treatment in both groups.Results The level of LSaO2 increased, and the levels of IAH, ODI, Epworth, Pittsburgh sleep index, serum IL-6, IL-18 and TNF-α decreased significantly after treatment (P<0.05), and the differences were more pronounced in the anti-supine group than in the CAPA group.Conclusion Anti-supine therapy is ideal for the treatment of obstructive sleep apnea-hypopnea syndrome.It not only can improve sleep quality and save money, but is convenient and practical, which has broad prospect in clinical application.