Objective Meige syndrome is an idiopathic movement disorder that manifests as craniofacial and often cervical dystonias .Deep brain stimulation (DBS) of the globuspallidusinternus (GPi) has emerged as a valid surgical option in the treatment of primary generalized or segmental dystonia .However , the experience with GPi-DBS in Meige syndrome is limited .Methods 3 patients with disabling Meige syndrome treated by bilateral GPi-DBS were followed for 4, 6 and 60 months . All patients were assessed before surgery and at the last follow-up after surgery using the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) which includes both the movement and disability scales . Results Bilateral GPi-DBS produceda sustained and long-lasting improvement in dystonia symptoms associated with Meige syndrome .At the last follow-up, the mean scores of BFMDRS movement and disability scales improved significantly by ( 78 ±3.1 )% ( range, 75% ~83%) and 100%, respectively .Conclusion Bilateral pallidal stimulationis a beneficial therapeutic option for long -term relief of the disabling dystonia symptoms in Meige syndrome .%目的： Meige综合征是一种特发性累及头面部的肌张力障碍，有时也会影响到颈部。脑深部电刺激（DBS）双侧苍白球内侧部（GPi）治疗肌张力障碍的报道比较多，但治疗Meige综合征的很少。方法对3例双侧GPi-DBS术后的Meige综合征患者进行随访4、6和60个月。所有患者术前术后均采用国际通用的Burke-Fahn-Marsden Dystonia Rating 量表（BFMDRS）评分，包括BFMDRS-Ⅰ（Movement 量表）和BFMDRS-Ⅱ（Disability量表）两个部分。结果3例Meige综合征患者手术后症状均有明显改善，BFMDRS第一部分和第二部分评分的改善率分别为（78±3．1）％（范围75％～83％）和100％。结论双侧GPi-DBS是治疗原发性Meige综合征的一种有效安全的手术方式。
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