目的 评价脑室线性结构在意识障碍(DOC)患者诊断和分级中的应用价值.方法 收集2015年1月至2015年12月就诊于中国人民解放军陆军总医院的20例DOC患者,由两名主治医师根据CRS-R评分量表将患者分为无反应觉醒综合征组(UWS)和微意识状态组(MCS).另选10例健康志愿者作为对照组.分析患者MRI T1图像的结果,测量数据并探索这些测量指标与CRS-R评分之间的相关性.结果 UWS组和MCS组的Huckman值和第三脑室宽度明显高于对照组(均P<0.05),而PDI指数和脑室指数则低于对照组(均P<0.05),除Evans值外其余各指标在UWS组和MCS组之间差别也具有统计学意义(均P<0.05).Huckman值和第三脑室宽度与CRS-R评分呈负相关,而PDI指数和脑室指数则相反.结论 脑室线性结构测量可以用于DOC患者意识水平的评估.%Objective To evaluate the value of cerebroventricular linear study of consciousness disorders in diagnosis and grading .Methods 20 disorders of consciousness ( DOC) were admitted in the Beijing PLA Army General Hospital from July , 2015 to Dec, 2015.The pations were assigned into unresponsive wakefulness syndrome ( UWS ) group , minimally consciousness state ( MCS ) group depending on CRS-R score and diagnosed by two chief doctors .10 healthy volunteers were assigned into control group .Analyzed the MRI T 1 images measured data and investigate the correlation between these indices and CRS-R score respectively .Results Huckman and width of the third encephalocoele of UWS and MCS group were significantly higher than those in the control group ( all P<0.05) .while PDI and cerebroventricular were lower than control group .The difference of these indexs between UWS and MCS were significant except Evans . Huckman and width of the third encephalocoele had significantly negative correlationship with CRS-R score between the two groups while PDI and cerebroventricular were opposite .Conclusion Cerebroventricular linear structure analysis could be used as a potential method to assess the degree of consciousness disorders .
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