腹腔镜胆囊切除术患者围术期氧化应激及血液黏滞度指标的变化

摘要

Objective To analyze and study the changes of oxidative stress and blood viscosity of patients with laparoscopic cholecystectomy during the perioperative period.Methods Fifty-six patients with laparoscopic cholecystectomy in our hospital from October 2011 to January 2013 were selected as observation group,and another 56 patients with open operation during the same period were selected as control group.The oxidative stress and blood viscosity indexes of the two groups on the 2nd day before the operation and 3rd and 7th day after the operation were detected and compared.Results The oxidative stress and blood viscosity indexes of the patients in the control group 2 days before operation,3 and 7 days after operation showed no statistically significant differences (P ＞0.05).While the oxidative stress indexes of the observation group 3 and 7 days after the operation were all better than those of the control group,with viscosity index lower than the control group (P ＜ 0.05).Conclusion The oxidative stress and blood viscosity of patients with laparoscopic cholecystectomy during the perioperative period are significantly better than those with open operation,and its perioperative and postoperative fluctuations are relatively better.%目的 探讨腹腔镜胆囊切除术患者围术期氧化应激及血液黏滞度的变化情况.方法 将2011年10月-2013年1月于本院行腹腔镜胆囊切除术治疗的56例患者设为观察组,另选取同期行开腹手术治疗的56例患者设为对照组.检测并比较2组患者术前2d,术后3、7d的氧化应激指标及血液黏滞度指标.结果 对照组患者术前2d,术后3、7d的氧化应激指标及血液黏滞度指标经比较差异均无统计学意义(P＞0.05);观察组术后3、7d的氧化应激指标均优于对照组,血液黏滞度指标均低于对照组(P＜0.05).结论 腹腔镜胆囊切除术患者围术期氧化应激及血液黏滞度均显著优于开腹手术患者,且其术前至术后的波动也相对较佳.