肝癌切除术后肝衰竭的研究现状

摘要

肝衰竭是肝癌切除术后最严重的并发症之一.血流动力学改变、胆盐失衡、免疫系统功能损伤均可引发肝癌切除术后肝衰竭,患者情况、肝脏情况、手术情况亦为相关危险因素.总结了肝癌切除术后肝衰竭的病因和影响因素,指出做好术前预防性工作,扩大术后残余肝体积,调整肝血流动力学失衡,优化围手术期治疗将有助于降低肝癌切除术后肝衰竭的发生率,进一步改善患者的预后,提高长期生存率.%Liver failure is one of the most serious complications after liver cancer resection.Hemodynamic changes,bile salt imbalance,and impaired immune function can cause liver failure after liver cancer resection,and related risk factors include patient,liver,and surgical conditions.This article summarizes the causes and influencing factors for liver failure after liver cancer resection and points out that prophylactic measures before surgery,expansion of remnant liver volume,adjustment of hemodynamic imbalance of the liver,and optimization of perioperative treatment help to reduce the incidence rate of liver failure after liver cancer resection and improve the prognosis and long-term survival of such patients.