BiPAP呼吸机治疗AECOPD合并II型呼吸衰竭的疗效观察

摘要

Objective To explore the clinical efficacy of bilevel positive airway pressure ( BIPAP ) respirator assisted ventilation in treatment of cases of acute exacerbation of chronic obstructive pulmonary disease ( AECOPD ) with type Ⅱ respiratory failure.Methods A total of 62 patients of acute exacerbation of chronic obstructive pulmonary disease with type Ⅱ respiratory failure were randomly allocated into two groups: trial group ( 32 cases ) and control group ( 30 cases ).The routine treatment including anti - infectious medication, cleaning airway and continuous inhalation of low concentration oxygen, and pneumatic analeptics was only given to patients of control group, but both BIPAP assisted ventilation and routine treatment were given to patients of trial group.Patients in these two groups were monitored for arterial blood gas parameters and changes of basic vital signs.Results Findings of heart rate, respiration rate, blood pH, PaO2 and PaCO2 in patients of two groups before treatment were compared with those after treatment, these parameters were obviously improved, their difference was significant ( P ＜ 0.05 ).There was significant difference ( P ＜ 0.05 ) in these findings between patients in trial group after treatment in comparison with those of patients in control group after treatment.Conclusion BIPAP assisted ventilation is certainly an effective measure for treatment of patients with AECOPD with type Ⅱ respiratory failure.%目的 探讨双水平气道正压无创通气(BIPAP)呼吸机在慢性阻塞性肺疾病急性加重期(AECOPD)并发Ⅱ型呼吸衰竭的临床应用.方法 62例AECOPD并发Ⅱ型呼吸衰竭患者随机分为治疗组(32例)和对照组(30例),治疗组除常规治疗外加用BiPAP呼吸机辅助通气治疗,对照组则予抗感染、通畅气道、持续低流量吸氧及应用呼吸兴奋剂等治疗,监测两组治疗前后血气参数和生命体征变化.结果 两组与治疗前相比心率、呼吸频率、pH、氧分压、二氧化碳分压均明显改善,差异均有显著性(P<0.05);治疗组(治疗后)与对照组(治疗后)相比有显著差异性(P<0.05).结论 BIPAP呼吸机辅助通气是治疗 AECOPD并发Ⅱ型呼吸衰竭的有效手段.