首页> 中文期刊> 《临床和实验医学杂志》 >多囊卵巢综合征与自身免疫性甲状腺炎的相关性研究

多囊卵巢综合征与自身免疫性甲状腺炎的相关性研究

         

摘要

目的:探讨多囊卵巢综合征( PCOS)与自身免疫性甲状腺炎( AIT)的相关性。方法选择84例PCOS患者为研究组,匹配84例健康妇女为对照组,检测甲状腺激素和甲状腺自身抗体水平,并比较。结果研究组血清TPO-Ab、TgAb水平均显著高于对照组。在84例PCOS中发现AIT患者共19例。PCOS+AIT患者的TSH水平显著高于对照组,而FT3、FT4水平未能在PCOS+AIT、PCOS患者和对照组中发现统计学差异。结论 PCOS患者AIT患病率显著高于正常人群,对PCOS患者应注意筛查甲状腺特异抗体。%Objective To explore the correlation between polycystic ovary syndrome( PCOS)and autoimmune thyroiditis( AIT). Meth-ods A total of 84 cases of PCOS were collected in study group,and 84 healthy women were allocated in control group. Blood levels of thyroid hor-mones and autoantibodies were detected and compared. Results The serum levels of TPOAb and TgAb in patients of study group were significant-ly higher than those of control group. A total of 19 patients with AIT were found in 84 patients with PCOS. Blood level of TSH in patients with P-COS and AIT was significantly higher,while there was no significant difference in blood levels of FT3 and FT4 among patients with PCOS and AIT, patients with PCOS and control group. Conclusion The morbidity of AIT in patients with PCOS is significantly higher than that of normal popula-tion. It is important to pay more attention to patients with PCOS for screening thyroid-specific antibodies.

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