Objective To compare the effects of sevoflureane and propofol on the maintenance of anesthesia in pediatric burn surgery. Methods Sixty pediatric burn patients were randomly divided into propofol group (group P) and sevoflureane group (group S). After tracheal intubation, anesthesia was maintained with infusion of propofol (3-8 mg·kg-1·h-1) in group P and inhalation of sevoflurane (l%-4%) in group S. Atracurium and fentanil were given intermittently when they were needed during the operation in both groups. Propofol and sevoflurane were discontinued five minutes before the end of surgery. The hemodynamics index, the time for recovery of spontaneously breathing, palinesthesia and extubation as well as the children's restlessness after surgery were recorded. Results After extubation, Spft declined significantly in group P, which was lower than that at the same point of group S (P<0. 05). The times for recovery of spontaneously breathing, palinesthesia and extubation were all shorter in group S than in group P (P<0. 01). Conclusion In pediatric burn surgery, sevoflureane maintenance anesthesia allows for a stabile circulatory system condition during the operation and fast recovery of spontaneously breathing, rapid awakening, timely extubation, and low incidence of restlessness. The anesthesia effect of sevoflureane is superior to propofol in the maintenance of anesthesia in pediatric burn surgery.%目的 比较七氟醚与丙泊酚用于小儿烧伤手术麻醉维持的效果.方法 择期手术烧伤患儿60例,随机分为丙泊酚组(P组)和七氟醚组(S组),每组30例.气管插管后P组泵注丙泊酚3～8 mg·kg-1·h-1维持麻醉,S组吸入1％～4％七氟醚维持麻醉；需要时均间断静注芬太尼和阿曲库铵.术毕前5 min停用丙泊酚和七氟醚.记录术中血流动力学指标以及术毕患儿自主呼吸恢复时间、苏醒时间、拔管时间、苏醒时躁动情况.结果 气管拔管后P组SpO2明显降低,且低于S组(P＜0.05).S组患儿自主呼吸恢复时间、拔管时间和苏醒时间均明显短于P组(P＜0.01).结论 七氟醚用于小儿烧伤手术麻醉维持循环稳定,术毕自主呼吸恢复快、苏醒迅速,拔管及时,躁动发生率低,麻醉效果优于丙泊酚.
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