紫外吸收光谱法测定羟基葫芦6脲与培氟沙星的包结作用

摘要

Perhydroxycucurbit[6]uril was synthesized according to the reference method,Interactions of perhydroxycucurbit[6]uril and pefloxacin were investigated by ultraviolet spectroscopy.The results indicate that perhydroxycucurbit[6]uril and pefloxacin formed 1：2 inclusion complexes.Absorbance and the density of gatifloxacin present favorable linear relaztion in the rage of the chroma of Pefloxacin from 10-8~10-5mol/L,the minimum detectability is 2×10-8mol/L,recovery rate is 102.4%.%参照文献方法合成羟基葫芦[6]脲,采用紫外分光光度法研究羟基葫芦[6]脲与培氟沙星在水溶液中的包结作用、包结比,以及回收率。结果表明,羟基葫芦[6]脲与培氟沙星在水溶液中可形成1∶2的包结物,吸光度与培氟沙星的浓度在10-8～10-5mol/L范围内呈良好的线性关系,最低检出限量为2×10-8mol/L,回收率为102.4%。