苯丙素苷及其类似物的合成研究

摘要

The regioselective acylation of unprotected phenylethyl glucoside with cinnamoyl chloride leads to 6-OH cinnamoylated glucoside.In this manner, thirteen phenylpropanoid glycoside analogs were designed and prepared.Their structure was confirmed by 1H NMR and 13C NMR spectra.%利用葡萄糖6位羟基活性较高的特性, 2-(取代)苯乙基-β-D-吡喃葡萄糖苷在低温条件下直接与(取代)肉桂酰氯反应,区域选择性地生成6位酰化的葡萄糖苷,利用此方法很方便的得到了13个苯丙素苷类似物,利用1H NMR 和13C NMR方法确证了他们的结构.