磺酸官能化三苯基磷负载磷钨酸催化合成异戊酸正丁酯

摘要

Butyl isovalerate has been synthesized by isovaleric acid and butanol with acidic ionic liquid as cat-alysts.Response Surface Methodology (RSM)was applied to optimize the synthesis of butyl isovalerate;the effects of various reaction conditions including alcohol /acid mole ratio,reaction time,ionic liquid amount and water carry-ing agent amount were also investigated.A Box -Behnken Experimental Design (BBD)was employed to search for the optimal yield of butyl isovalerate;the optimized reaction conditions were n (butanol)∶n (isovaleric acid)of 1.15∶1,reaction time of 80 min,amount of catalyst of 8% of acid and water -carrying agent of 10 mL.On the con-ditions,the best esterification rate could reach 89.52%,basically in line with the values predicted by the mathemati-cal model.The ionic liquids could be recycled and reused for 5 times without obvious degradation in activity indica-ting that the catalysts have a good repetition.%以异戊酸和正丁醇为原料，酸性离子液体为催化剂，合成异戊酸正丁酯。选取醇酸物质的量比、反应时间、离子液体用量、带水剂量4个因素进行中心组合优化，运用响应面法得出合成异戊酸正丁酯的最佳工艺条件为：醇酸物质的量比1．15∶1，反应时间为80 min，离子液体用量为异戊酸的8％，带水剂量10 mL，在此最佳反应条件下异戊酸正丁酯的酯化率为89．52％，结果与模型预测值基本相符。将离子液体回收并重复使用5次，催化活性无明显降低，表明其具有良好的重复使用性。