2230例变应性疾病患者血清特异性抗体测定分析

摘要

Objective To detect serum specific IgE in allergic diseases for clinical diagnosis and therapy. Methods The serum specific IgE and total IgE ( slgE) were detected by enzyme immunoassay in 2 230 patients. Results The dermatophagoides farinae (28.3% ) and pteronyssinus( 26. 6% ) were the most common allergen in 2 230 patients, followed by Artemisia(14. 9% ) , cat hair dander(9% ) , beef and mutton(9% ), cockroaches(8.3% ) , seafood(8. 1% ), fungi(6.6% ) , milk(6. 1% ), short ragweed(5.6% ), peanuts, cashew nuts(4.6% ), elm, sycamore, willow, cottonwood(3. 8% ) , egg white(3. 8% ) , soybeans(3. 1% ). The positive rate of total IgE was 46. 9%. Conclusion The detection of serum specific IgE and total IgE can help to find the corresponding clinical allergy, and provide evidences for prevention, diagnosis and therapy of allergic diseases.%目的 检测变应性疾病血清特异性抗体筛选相关过敏原,为临床诊断和治疗提供依据.方法 采用过敏原检测系统,对2 230例变应性疾病患者的血清特异性免疫球蛋白E( immunoglobtlin,IgE)及总IgE水平进行了检测.结果 2 230例变应性疾病患者中过敏原以屋尘螨(28.3%)、粉尘螨(26.6%)为最高,其后依次为蒿(14.9%)、猫毛皮屑(9%)、牛羊肉(9%)、蟑螂(8.3%)、鱼虾蟹(8.1%)、霉菌(6.6%)、牛奶(6.1%)、矮豚草(5.6%)、腰果花生(4.6%)、榆、梧桐、柳、三角叶杨(3.8%)、鸡蛋白(3.8%)、黄豆(3.1%)；总IgE阳性率为46.9%.结论 血清特异性IgE及总IgE的检测分析可以帮助临床寻找相应过敏原,为变应性疾病的预防、诊断和治疗提供依据.