溶胶－凝胶法制备纳米双相磷酸钙生物陶瓷粉体的研究

摘要

制备纳米级双相磷酸钙（BCP）生物陶瓷粉体。采用溶胶－凝胶法，以（CH3 O）3 P 和 Ca（NO3）2·4H2 O为主要原料，通过钙 XRD、SEM、TEM等检测方法，探索煅烧温度及原料初始 Ca ／P 比对产物组成以及粉体粒径的影响。煅烧温度对产物钙磷比、颗粒尺寸均有一定影响，调节反应物初始 Ca ／P 可控制产物两相组成比例，进而调节产物生物活性、降解速度等特性。通过溶胶－凝胶法制备了粒径为50～100纳米、粒径和组成可控的双相磷酸钙粉体。%To prepare nano -sized biphasic calcium phosphate (BCP)bioceramic powders.BCP was prepared by a sol -gel method starting from (CH3 O)3 P and Ca(NO3 )24H2 O.The product was analyzed using XRD,SEM and TEM.The influences of the heat treating temperature and the starting Ca/P mol ratio on the composition and particle size of BCP product were investigated.The heat treating temperature had certain influence on the Ca/P mol ratio and the particle size of the product.The phase constitution which decides the bioactivity and bio -degradation of the product could be controlled by the starting Ca/P mol ratio.Nano sized biphasic cal-cium phosphate (BCP)bioceramic powders with range from 50nm to 100nm can be derived from sol -gel method.The particle size and the constitution of the product can be controlled by the process condition.