汉、维语动词产生任务的脑因果效应差异研究

摘要

To explore the differences of effective connectivity while verbal generation task is respectively performed by people in Chi -nese (NH group) as well as in Uighur (NW group).Functional MRI data was acquired when verbal generation task was conducted on n-ative Chinese and native Uighur volunteers .After detecting the activated brain region , we selected the left Caudate (CAU.L) as ROI(re-gion of interesting ) , then chose the Granger Causality Analysis to perform the effective connectivity analysis .Compared with NW group , NH group showed increased inflows from the right frontal and parietal lobe , as well as the left frontal , limbic and occipital cortex to CAU.L.Besides, NH group also showed increased outflows from CAU .L to the right cingulate cortex and middle temporal cortex .While performing the verbal generation task , NH group shows increased effective connectivity between CAU .L and the regions related to visual sense, memory and semantics .NH group invokes more brain regions and shows more complicated information flows while carrying out the verbal generation task , it is presumed that NH group exists a more complex neural mechanism of language than NW group .%探讨以汉语、维语为母语的人群进行动词产生任务时的脑区间因果效应差异.对以母语为汉语(NH)和维语(NW)的受试者进行动词产生任务的功能磁共振(functional magnetic resonance imaging,fMRI)fMRI数据采集,对实验数据进行脑区激活分析后选取左侧尾状核(CAU.L)为种子点,选用Granger因果分析方法(granger causality analysis,GCA)进行有效连接分析.与维语组相比,汉语组自右侧大脑额叶、顶叶,左侧额叶、边缘叶、枕叶对CAU.L的GC(granger causal,GC)内向信息流显著增强;此外,汉语组自CAU.L对右侧扣带及颞中回的GC外向流增强.汉语组执行动词产生任务时视觉、记忆、语义相关脑区与CAU.L间有效连接强度普遍高于维语组,汉语组在动词产生任务时调用更多脑区、信息流更复杂,推测汉语组动词产生的语言神经机制比维语组要更为复杂.