瑞舒伐他汀联合尼麦角林对颈动脉狭窄后认知障碍的治疗效果

摘要

目的:探讨瑞舒伐他汀联合尼麦角林在治疗颈动脉狭窄后认知障碍的临床效果.方法:选取颈动脉狭窄后认知障碍患者108例,按数字表法分为观察组55例和对照组53例.对照组仅予尼麦角林,观察组予瑞舒伐他汀联合尼麦角林,应用简易智能状态检查表(MMSE)和日常生活活动能力量表(ADL)评价2组患者的认知和活动能力,比较2种治疗方法的临床疗效.结果:2组患者治疗前MMSE和ADL评分差异均无统计学意义(P>0.05);2组患者治疗后MMSE和ADL评分均较治疗前明显改善(P0. 05),the MMSE and ADL scores in two groups were significantly improved(P<0. 01) and the increasing degree of the MMSE and ADL scores in observation group were significantly higher than those in control group after treatment(P<0. 01). The clinical total effective rate in observation group(96. 36%) was significantly better than that in control group(79. 25%)(P<0. 01). Conclusions:The treatment of cognitive impairment after carotid stenosis with rosuvastatin combined with nicergoline can effectively improve the cognitive function and activities of daily living. The treatment effects of rosuvastatin combined with nicergoline is significantly better than that of nicergoline, which is worthy of application in clinical.