稀土元素及其化合物对机体损害作用的研究进展

摘要

The rare earth elements ( REEs) are composed of a set of 17 chemical elements, including the lanthanide series from lanthanum (La) to lutetium (Lu), as well as scandium (Sc) and yttrium (Y) of the similar nature in the periodic table.REEs and their compounds which are of special physical and chemical properties have been widely used in such fields, animal husbandry, fishery, industry, medicine, environmen-tal protection, electronics and new material application etc.that the number of people in direct contact with rare earth are rising rapidly as a conse-quence of the constantly expansive application of them, contributing to the increasing emergence of damages to human body.There is growing con-cern among people for the effect of RE on the environment, ecology and human health, as well as its short and long term harmful effects.Rare earth compounds have a damaging influence on human body, which is reviewed from the perspective of human body, tissues, cells, level of DNA in this article so as to provide a reference for the safe application of rare earth compounds .%稀土元素（ rare earth elements， REEs）由17种化学元素组成，包括从镧（ La）到镥（ Lu）的15种镧系元素以及性质十分相似的钪（ Sc）和钇（ Y）。稀土元素及其化合物具有特殊的理化性质，广泛应用于畜牧业、渔业、工业、医药、环保、电子、新材料制造等多种领域，其应用领域仍在不断扩大，导致直接接触稀土的人群迅速增加，对机体的损害作用也日益显现。稀土对环境、生态和人体健康的影响以及近期和远期损害作用越来越引起人们的关注。本文从人体、组织、细胞、DNA水平对稀土化合物对机体损害作用进行综述，以便对稀土化合物的安全应用提供参考。