尼莫地平在急性大脑中动脉M1段闭塞及其侧枝循环的治疗效果观察

摘要

Objective To explore the effect of nimodipine on acute occlusion of M1 segment of middle cerebral artery and collateral cir-culation. Method 80 patients with acute cerebral infarction caused by occlusion of M1 segment of middle cerebral were selected and ran-domly divided into observation group and control group. Two groups were given conventional treatment,the observation group was given ni-modipine. The nerve function defect and activities of daily living ability improvement were observed at the admission and after treatment for 2 weeks. Results The scores of nerve function defect and activities of daily living ability in the observation group after treatment for 2 weeks. compared with those in control group after treatment for 2 weeks. the difference was statistically significant( P<0. 05). Conclusion Nimodipine on acute cerebral infarction caused by occlusion of M1 segment of middle cerebral has significant effect,and may improve the collateral circulation,the therapy is worthy of learning.%目的：探讨尼莫地平在急性大脑中动脉M1段闭塞及其侧枝循环的治疗效果。方法：选择80例急性大脑中动脉M1段闭塞所致脑梗死患者，随机分为观察组和对照组。两组均给予常规治疗，观察组同时给予尼莫地平治疗。观察两组患者入院时、治疗2周后的神经功能缺损和日常生活活动能力改善情况。结果：观察组治疗2周后的神经功能缺损评分及日常生活活动能力评分分别与对照组治疗2周后的神经功能缺损评分及日常生活活动能力评分比较，差异有统计学意义（ P<0.05）。结论：尼莫地平在急性大脑中动脉M1段闭塞所致脑梗死中临床效果显著，有助于改善其侧枝循环，值得借鉴。