四连康及蒙托石散治疗母乳性黄疸的疗效研究

摘要

目的：探讨四连康（双歧杆菌四联活菌）、蒙脱石散治疗婴儿黄疸的疗效分析。方法：将85例母乳性黄疸病例随机分为4组，A组对照组（20例），B组四连康组（25例），C组蒙脱石组（20例），D组四连康联合蒙脱石组（20例），四组均停母乳。观察其黄疸消退情况，治疗前后胆红素水平变化。结果：5d后监测血胆红素水平，B组、C组、D组均较对照组血胆红素下降明显，差异有统计学意义（ P﹤0.01），黄疸消退平均时间较对照组明显提前，差异有统计学意义（ P﹤0.01）。不同治疗组间黄疸消退时间及胆红素下降值亦不相同。结论：四连康和蒙脱石散治疗婴儿母乳性黄疸均有显著效果，可促进胆红素排泄，缩短患儿住院治疗时间，且两者疗效相当，联合用药效果更明显。%Objective To observe and analyze the effects of Combined Bifidobacterium,Lactobacillus,Enterococcus and Bacillus cereus Tablets,Live and Montmorillonite powder in the therapy of jaundice. Method 85 patients with breast milk jaundice were divided randomly into four groups:A( control group)、B( the group of Combined Bifidobacterium,Lactobacillus,Enterococcus and Bacillus cereus Tablets, Live)、C( the group of Montmorillonite powder )and D( the group of Combined Bifidobacterium,Lactobacillus,Enterococcus and Bacillus cereus Tablets,Live combined with Montmorillonite powder),the four groups all stopped breastfeeding. Detected the bilirubin concentration in the blood and jaundice time after the four treatments. Results Compared to control group and observation groups,the observation groups in the reduction of time were fast and reduction of bilirubin levels were higher than the control group. But the effects were different among the observation groups. Conclusion Combined Bifidobacterium,Lactobacillus,Enterococcus and Bacillus cereus Tablets,Live and Montmo-rillonite powder could advance the excretion of bilirubin,shorter hospital stay. There is no difference between the two treatments and combi-nation therapy is more effective.