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USE OF TOPOTECAN IN THE MANUFACTURE OF A MEDICAMENT FOR USE IN THE TREATMENT OF OVARIAN CANCER
USE OF TOPOTECAN IN THE MANUFACTURE OF A MEDICAMENT FOR USE IN THE TREATMENT OF OVARIAN CANCER
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机译:在治疗卵巢癌的药物中使用托托替康
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摘要
The invention relates to a pharmaceutical composition comprising topotecan, for use in the treatment of ovarian cancer in a human afflicted therewith, wherein the composition is for parenteral administration to such human employing a course of therapy of from 1.0 to 2.5 mg (e.g. about 1.5 to about 2 mg) of topotecan/m 2 of body surface area per day for about five consecutive days. The invention also relates to a pharmaceutical composition comprising topotecan, for use in the treatment of ovarian cancer in a human afflicted therewith, wherein the composition is for oral administration to such human employing a course of therapy of from 1.5 to 5.0 mg of topotecan/m 2 of body surface area per day for about five consecutive days. The pharmaceutical composition can be an oral or parenteral pharmaceutical composition comprising topotecan and an inert, pharmaceutically acceptable carrier or diluent.
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机译:本发明涉及包含托泊替康的药物组合物,其用于治疗受其折磨的人的卵巢癌,其中所述组合物用于通过1.0至2.5mg(例如约1.5至2.5mg)的治疗过程对此类人肠胃外给药。每天约2毫克的拓扑替康/ m 2身体表面积,连续约五天。本发明还涉及包含托泊替康的药物组合物,其用于治疗受其折磨的人的卵巢癌,其中所述组合物用于以1.5至5.0mg托泊替康/ m 3的治疗过程口服给予该人每天约有2个人体表面积连续5天。药物组合物可以是包含托泊替康和惰性的药学上可接受的载体或稀释剂的口服或肠胃外药物组合物。
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