目的：对腹腔镜胆囊切除手术（LC）治疗的患者采用脑电双频指数（BIS）指导下丙泊酚 TCI 联合瑞芬太尼麻醉的效果进行分析探究。方法：选取160例胆囊切除手术治疗的患者作为研究对象，将其平均分为试验组和对照组，对照组采用丙泊酚 TCI 联合瑞芬太尼药物麻醉，试验组给予脑电双频指数（BIS）指导下行丙泊酚 TCI 联合瑞芬太尼药物麻醉，对比分析麻醉后患者的恢复时间情况。结果：试验组研究对象的瑞芬太尼用药剂量（0.102±0.004）μg/（ kg·min）及喉罩拔出的时间（8.4±1.3）min、睁眼的时间（7.6±2.1）min 与对照组研究对象的瑞芬太尼用药剂量（0.598±0.007）μg/（kg·min）及喉罩拔出的时间（12.2±1.5）min、睁眼的时间（13.3±2.4）min，差异有统计学意义（P ﹤0.05）。结论：采用脑电双频指数（BIS）指导下丙泊酚 TCI联合瑞芬太尼麻醉的效果显著，安全可靠，值得推广。%Objective To analyze and explore the effect of TCI combined with remifentanil anesthesia on patients treated with Laparo-scopic cholecystectomy(LC). Method 160 cases of cholecystectomy surgery patients were selected as research object. They were divided into experimental group and control group,control group was treated with TCI of propofol combined with remifentanil drug anesthe-sia. Experimental group was given bispectral index(BIS)guided TCI of propofol combined with remifentanil fentanyl anesthesia. Anesthesia patients recovery time was analyzed and compared. Results There were statistical significance between experiment group's remifentanil dos-age(0. 102 ± 0. 004)μg/(kg·min)and laryngeal cover(7. 6 ± 2. 1)min pulled out of time(8. 4 ± 1. 3)min,the time of eye opening and control group's remifentanil dosage(0. 598 ± 0. 007)μg/(kg·min)and laryngeal mask(13. 3 ± 2. 4)min pulled out of time(12. 2 ± 1. 5)min,the results had statistical significance(P ﹤ 0. 05). Conclusion The effect of propofol combined with remifentanil anesthesia under guidance of TCI(BIS)is significant,it is worth popularizing with its safety and reliability.
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