目的：探究改良血液灌流联合血液透析的预充方法。方法：选取进行维持性血液透析的慢性肾衰患者230例作为研究对象，将其随机分为对照组和试验组，平均每组115例。对照组予以传统的血液灌流联合血液透析的预充方法，试验组予以改良后的血液灌流联合血液透析的预充方法。记录治疗后灌流器凝血情况、治疗前后患者血磷含量及甲状旁腺激素变化，并进行比较。结果：通过不同的预充方法治疗后，试验组与对照组相比，灌流器凝血及血磷含量及甲状旁腺激素下降水平无明显差异。结论：使用改良血液灌流联合血液透析的预充方法，不但能有效的降低甲状旁腺激素含量及血磷浓度，也没有增加灌流器凝血风险，还能有效节约预充时间，并减轻了患者的经济负担，建议在临床上大力推广。%Objective To explore the modified method of hemoperfusion combined with hemodialysis priming. Method 230 cases of chro-nic renal failure who did maintenance hemodialysis were selected as the research object,and they were randomly divided into control group and experimental group,each group had 115 cases,the control group was given the traditional hemoperfusion combined with hemodialysis,the ex-perimental group was treated with hemoperfusion combined with hemodialysis which had improved. Hemoperfusion,blood coagulation of pa-tients with phosphorus and parathyroid hormone changes before and after the treatment were recorded and compared. Results There were no significant difference between the perfusion of blood coagulation and blood phosphorus and parathyroid hormone level in two groups after dif-ferent pre charging methods. Conclusion Priming method using the modified hemoperfusion combined with hemodialysis,not only can decrease the parathyroid hormone content and phosphorus concentration effectively,but also don't increase the perfusion in the risk of blood clots,as well as effectively save the pre charge time,and reduce the economic burden of the patients,we suggest to popularize in clinical.
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